Automatized smoking-related action schemata are reflected by reduced fMRI activity in sensorimotor brain regions of smokers.

ABSTRACT: In the later stages of addiction, automatized processes play a prominent role in guiding drug-seeking and drug-taking behavior. However, little is known about the neural correlates of automatized drug-taking skills and drug-related action knowledge in humans. We employed functional magnetic resonance imaging (fMRI) while smokers and non-smokers performed an orientation affordance task, where compatibility between the hand used for a behavioral response and the spatial orientation of a priming stimulus leads to shorter reaction times resulting from activation of the corresponding motor representations. While non-smokers exhibited this behavioral effect only for control objects, smokers showed the affordance effect for both control and smoking-related objects. Furthermore, smokers exhibited

SUBMITTER: Isik AI 

PROVIDER: S-EPMC5493837 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature