A new computational method for the detection of horizontal gene transfer events.

ABSTRACT: In recent years, the increase in the amounts of available genomic data has made it easier to appreciate the extent by which organisms increase their genetic diversity through horizontally transferred genetic material. Such transfers have the potential to give rise to extremely dynamic genomes where a significant proportion of their coding DNA has been contributed by external sources. Because of the impact of these horizontal transfers on the ecological and pathogenic character of the recipient organisms, methods are continuously sought that are able to computationally determine which of the genes of a given genome are products of transfer events. In this paper, we introduce and discuss a novel computational method for identifying horizontal transfers that relies on a gene's nucleotide comp

SUBMITTER: Tsirigos A 

PROVIDER: S-EPMC549390 | biostudies-literature | 2005

REPOSITORIES: biostudies-literature