BMI prediction within a Korean population.

ABSTRACT:

Background

Body Mass Index (BMI) is widely regarded as an important clinical trait for obesity and other diseases such as Type 2 diabetes, coronary heart disease, and osteoarthritis.

Methods

This study uses 6,011 samples of genotype data from ethnic Korean subjects. The data was retrieved from the Korea Association Resource. To identify the BMI-related markers within the Korean population, we collected genome-wide association study (GWAS) markers using a GWAS catalog and also obtained other markers from nearby regions. Of the total 6,011 samples, 5,410 subjects were used as part of a single nucleotide polymorphism (SNP) selection set in order to identify the overlapping BMI-associated SNPs within a 10-fold cross validation.

Results

We selected nine SNPs (rs12566985

SUBMITTER: Lee JS 

PROVIDER: S-EPMC5493974 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature