Construction, internal validation and implementation in a mobile application of a scoring system to predict nonadherence to proton pump inhibitors.

ABSTRACT:

Background

Other studies have assessed nonadherence to proton pump inhibitors (PPIs), but none has developed a screening test for its detection.

Objectives

To construct and internally validate a predictive model for nonadherence to PPIs.

Methods

This prospective observational study with a one-month follow-up was carried out in 2013 in Spain, and included 302 patients with a prescription for PPIs. The primary variable was nonadherence to PPIs (pill count). Secondary variables were gender, age, antidepressants, type of PPI, non-guideline-recommended prescription (NGRP) of PPIs, and total number of drugs. With the secondary variables, a binary logistic regression model to predict nonadherence was constructed and adapted to a points system. The ROC curve, with its area (A

SUBMITTER: Mares-Garcia E 

PROVIDER: S-EPMC5494169 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature