Surviving heat shock: control strategies for robustness and performance.

ABSTRACT: Molecular biology studies the cause-and-effect relationships among microscopic processes initiated by individual molecules within a cell and observes their macroscopic phenotypic effects on cells and organisms. These studies provide a wealth of information about the underlying networks and pathways responsible for the basic functionality and robustness of biological systems. At the same time, these studies create exciting opportunities for the development of quantitative and predictive models that connect the mechanism to its phenotype then examine various modular structures and the range of their dynamical behavior. The use of such models enables a deeper understanding of the design principles underlying biological organization and makes their reverse engineering and manipulation both pos

SUBMITTER: El-Samad H 

PROVIDER: S-EPMC549435 | biostudies-literature | 2005 Feb

REPOSITORIES: biostudies-literature