Polymorphism in the intron 20 of porcine O-linked N-acetylglucosamine transferase.

ABSTRACT:

Objective

O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of O-GlcNAc and GlcNAcylation has extensive crosstalk with phosphorylation to regulate signaling and transcription. Pig OGT is located near the region of chromosome X that affects follicle stimulating hormone level and testes size. The objective of this study was to find the variations of OGT between European and Chinese pigs.

Methods

Pigs were tested initially for polymorphism in OGT among European and Chinese pigs by polymerase chain reaction and sequencing at the U.S. Meat Animal Research Center (USMARC). The polymorphism was also determined in an independent population of pigs including European and Chinese Meishan (ME) breeds at the National Institute of Anima

SUBMITTER: Kim JG 

PROVIDER: S-EPMC5494481 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature