A Meta-Analysis of Choroidal Thickness Changes in Unilateral Amblyopia.

ABSTRACT:

Purpose

To date, the topic of amblyopic changes remains controversial. Therefore, a systematic review and meta-analysis were carried out to evaluate choroidal changes in unilateral amblyopia.

Methods

Major literature databases were searched for amblyopia-relevant studies. Using enhanced depth imaging optical coherence tomography (EDI-OCT), the primary outcome parameters examined were subfoveal choroidal thickness (SFCT) and different choroidal thickness (CT) positions. Efficacy estimates were evaluated by weighted mean difference (WMD) and 95% confidence interval (CI) for choroidal-associated changes. We performed subgroup analysis and metaregression analysis to examine potential sources of heterogeneity.

Results

Eleven cross-sectional studies that included a total of

SUBMITTER: Liu Y 

PROVIDER: S-EPMC5494565 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature