Ontology highlight
ABSTRACT:
SUBMITTER: Slanchev K
PROVIDER: S-EPMC549510 | biostudies-literature | 2005 Mar
REPOSITORIES: biostudies-literature
Slanchev Krasimir K Stebler Jürg J de la Cueva-Méndez Guillermo G Raz Erez E
Proceedings of the National Academy of Sciences of the United States of America 20050223 11
The progenitors of the gametes, the primordial germ cells (PGCs) are typically specified early in the development in positions, which are distinct from the gonad. These cells then migrate toward the gonad where they differentiate into sperms and eggs. Here, we study the role of the germ cells in somatic development and particularly the role of the germ line in the sex differentiation in zebrafish. To this end, we ablated the germ cells using two independent methods and followed the development o ...[more]