Five-year changes in cardiac structure and function in patients with rheumatoid arthritis compared with the general population.

ABSTRACT:

Background

Patients with rheumatoid arthritis (RA) have increased risk of heart failure with preserved ejection fraction. The development and progression of left ventricular dysfunction before onset of clinical heart failure are unknown. The objective of this study was to evaluate longitudinal changes in cardiac structure and function of patients with RA compared with persons in the general population.

Methods

A prospective longitudinal study of a population-based cohort of 160 patients with RA and a population-based cohort of 1391 persons without RA (non-RA cohort) was performed. Each participant underwent 2-dimensional, pulsed-wave tissue Doppler echocardiography at baseline and after 4 to 5years of follow-up. Age- and sex-adjusted linear regression models were used to tes

SUBMITTER: Davis JM 

PROVIDER: S-EPMC5495559 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature