Coat colour phenotype of Qingyu pig is associated with polymorphisms of melanocortin receptor 1 gene.

ABSTRACT:

Objective

Qingyu pig, a Chinese indigenous pig breed, exhibits two types of coat colour phenotypes, including pure black and white with black spotting respectively. Melanocortin receptor 1 (MC1R) and agouti signaling protein (ASIP) are two widely reported pivotal genes that significantly affect the regulation of coat colour. The objectives of this study were to investigate whether the polymorphisms of these two genes are associated with coat colour and analyze the molecular mechanism of the coat colour separation in Qingyu pig.

Methods

We studied the phenotype segregation and used polymerase chain reaction amplification and Sanger sequencing to investigate the polymorphism of MC1R and ASIP in 121 Qingyu pigs, consisting of 115 black and 6 white wi

SUBMITTER: Wu X 

PROVIDER: S-EPMC5495671 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature