Absolute structure determination of compounds with axial and planar chirality using the crystalline sponge method.

ABSTRACT: The absolute stereochemistry of compounds with axial and planar chirality is successfully determined by the crystalline sponge method without crystallization or derivatization of the compounds. This method is applied to absolute structure determination in the asymmetric synthesis of unique compounds with axial and planar chirality.

SUBMITTER: Yoshioka S 

PROVIDER: S-EPMC5496191 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature