Piperine enhances carbohydrate/fat metabolism in skeletal muscle during acute exercise in mice.

ABSTRACT:

Background

Exercise promotes energy metabolism (e.g., metabolism of glucose and lipids) in skeletal muscles; however, reactive oxygen species are also generated during exercise. Various spices have been reported to have beneficial effects in sports medicine. Here, we investigated the effects of piperine, an active compound in black pepper, to determine its effects on metabolism during acute endurance exercise.

Methods

ICR mice (n = 18) were divided into three groups: nonexercise (CON), exercise (EX), and exercise with piperine (5 mg/kg) treatment (EP). Mice were subjected to enforced exercise on a treadmill at a speed of 22 m/min for 1 h. To evaluate the inflammatory responses following exercise, fluorescence-activated cell sorting analysis was performed to monitor ch

SUBMITTER: Kim J 

PROVIDER: S-EPMC5496355 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature