Genetic diversity of Plasmodium falciparum populations in southeast and western Myanmar.

ABSTRACT:

Background

The genetic diversity of malaria parasites reflects the complexity and size of the parasite populations. This study was designed to explore the genetic diversity of Plasmodium falciparum populations collected from two southeastern areas (Shwekyin and Myawaddy bordering Thailand) and one western area (Kyauktaw bordering Bangladesh) of Myanmar.

Methods

A total of 267 blood samples collected from patients with acute P. falciparum infections during 2009 and 2010 were used for genotyping at the merozoite surface protein 1 (Msp1), Msp2 and glutamate-rich protein (Glurp) loci.

Results

One hundred and eighty four samples were successfully genotyped at three genes. The allelic distributions of the three genes were all significantly different among three areas. MAD20

SUBMITTER: Soe TN 

PROVIDER: S-EPMC5496439 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature