White matter integrity in dyskinetic cerebral palsy: Relationship with intelligence quotient and executive function.

ABSTRACT:

Background

Dyskinetic cerebral palsy (CP) is one of the most disabling motor types of CP and has been classically associated with injury to the basal ganglia and thalamus. Although cognitive dysfunction is common in CP, there is a paucity of published quantitative analyses investigating the relationship between white matter (WM) microstructure and cognition in this CP type.

Aims

This study aims (1) to compare brain WM microstructure between people with dyskinetic CP and healthy controls, (2) to identify brain regions where WM microstructure is related to intelligence and (3) to identify brain regions where WM microstructure is related to executive function in people with dyskinetic CP and (4) to identify brain regions where the correlations are different between controls and

SUBMITTER: Laporta-Hoyos O 

PROVIDER: S-EPMC5496484 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature