Influence of genetic variants associated with body mass index on eating behavior in childhood.

ABSTRACT:

Objective

Childhood eating behaviors are associated with body mass index (BMI). Recent genome-wide association studies have identified many single-nucleotide polymorphisms (SNPs) associated with adult and childhood BMI. This study hypothesized that these SNPs also influence eating behavior.

Methods

In a population-based prospective cohort study among 3,031 children (mean age [standard deviation]: 4.0 [0.1] years), two weighted genetic risk scores, based on 15 childhood and 97 adult BMI SNPs, and ten individual appetite- and/or satiety-related SNPs were tested for association with food fussiness, food responsiveness, enjoyment of food, satiety responsiveness, and slowness in eating.

Results

The 15 SNP-based childhood BMI genetic risk score was not associated with the e

SUBMITTER: Monnereau C 

PROVIDER: S-EPMC5496668 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature