N-Heterocyclic Carbene and Chiral Bronsted Acid Cooperative Catalysis for a Highly Enantioselective [4+2] Annulation.

ABSTRACT: A chiral NHC/Brønsted acid cooperative catalysis system has been developed for asymmetric annulation of functionalized benzaldehydes and activated ketones through dearomative generation of dienolate.

SUBMITTER: Chen DF 

PROVIDER: S-EPMC5496987 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature