Plasma mannose level, a putative indicator of glycogenolysis, and glucose tolerance in Japanese individuals.

ABSTRACT:

Aims/introduction

Mannose is a monosaccharide constituent of glycoproteins and glycolipids. Experiments in rats have shown previously that the plasma mannose level decreases after glucose load, but does not decrease in diabetic rats, and that hepatic glycogenolysis is a source of this plasma mannose; however, these results are not fully elucidated in humans. Plasma mannose levels before/after glucose loading in humans with various degrees of glucose intolerance were examined to analyze their association with clinical factors.

Materials and methods

The 75-g oral glucose tolerance test was carried out in Japanese individuals not taking diabetes medications. Participants were classified into normal glucose tolerance, impaired glucose metabolism and diabetes mellitus groups. Ins

SUBMITTER: Yoshimura K 

PROVIDER: S-EPMC5497030 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature