Unstable bodyweight and incident type 2 diabetes mellitus: A meta-analysis.

ABSTRACT:

Aims/introduction

The present meta-analysis aimed to clarify the association of unstable bodyweight with the risk of type 2 diabetes mellitus, an association that has been controversial among longitudinal studies.

Materials and methods

An electronic literature search using EMBASE and MEDLINE was followed up to 31 August 2016. The relative risks (RRs) of type 2 diabetes mellitus in individuals with unstable bodyweight were pooled using the inverse variance method.

Results

Eight studies were eligible for the meta-analysis. The median duration of measurements of weight change and follow-up years for ascertaining type 2 diabetes mellitus were 13.5 and 9.4 years, respectively. The pooled RR for the least vs most stable category was 1.33 (95% confidence interval 1.12-1.57).

SUBMITTER: Kodama S 

PROVIDER: S-EPMC5497032 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature