Efficacy and safety of premixed insulin analogs in Asian patients with type 2 diabetes: A systematic review.

ABSTRACT:

Aims/introduction

The primary aim of this systematic review was to provide an overview of the efficacy and safety of premixed insulin analogs in Asians, specifically East Asians, with type 2 diabetes.

Material and methods

The MEDLINE, Embase, Cochrane Library and ClinicalTrials.gov databases were searched from 1 January 1995 to 26 November 2015. Randomized controlled trials involving East Asians with type 2 diabetes treated with any premixed insulin analog were included. Major comparator treatments were basal insulin and basal-bolus insulin. Comparisons were also made between East Asian and Caucasian patients. The primary efficacy outcome was glycated hemoglobin change from baseline to end-point. The primary safety outcome was the incidence of hypoglycemia.

Results

A

SUBMITTER: Sheu WH 

PROVIDER: S-EPMC5497049 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature