A Prototype High-Resolution Small-Animal PET Scanner Dedicated to Mouse Brain Imaging.

ABSTRACT:

Unlabelled

We developed a prototype small-animal PET scanner based on depth-encoding detectors using dual-ended readout of small scintillator elements to produce high and uniform spatial resolution suitable for imaging the mouse brain.

Methods

The scanner consists of 16 tapered dual-ended-readout detectors arranged in a 61-mm-diameter ring. The axial field of view (FOV) is 7 mm, and the transaxial FOV is 30 mm. The scintillator arrays consist of 14 × 14 lutetium oxyorthosilicate elements, with a crystal size of 0.43 × 0.43 mm at the front end and 0.80 × 0.43 mm at the back end, and the crystal elements are 13 mm long. The arrays are read out by 8 × 8 mm and 13 × 8 mm position-sensitive avalanche photodiodes (PSAPDs) placed at opposite ends of the array. Standard nuclear-inst

SUBMITTER: Yang Y 

PROVIDER: S-EPMC5497697 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature