Influence of seizures on early development in tuberous sclerosis complex.

ABSTRACT:

Objective

Epilepsy is commonly seen in Tuberous Sclerosis Complex (TSC). The relationship between seizures and developmental outcomes has been reported, but few studies have examined this relationship in a prospective, longitudinal manner. The objective of the study was to evaluate the relationship between seizures and early development in TSC.

Methods

Analysis of 130 patients ages 0-36months with TSC participating in the TSC Autism Center of Excellence Network, a large multicenter, prospective observational study evaluating biomarkers predictive of autism spectrum disorder (ASD), was performed. Infants were evaluated longitudinally with standardized evaluations, including cognitive, adaptive, and autism-specific measures. Seizure history was collected continuously throughou

SUBMITTER: Capal JK 

PROVIDER: S-EPMC5497719 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature