A tail of two voltages: Proteomic comparison of the three electric organs of the electric eel.

ABSTRACT: The electric eel (Electrophorus electricus) is unusual among electric fishes because it has three pairs of electric organs that serve multiple biological functions: For navigation and communication, it emits continuous pulses of weak electric discharge (<1 V), but for predation and defense, it intermittently emits lethal strong electric discharges (10 to 600 V). We hypothesized that these two electrogenic outputs have different energetic demands reflected by differences in their proteome and phosphoproteome. We report the use of isotope-assisted quantitative mass spectrometry to test this hypothesis. We observed novel phosphorylation sites in sodium transporters and identified a potassium channel with unique differences in protein concentration among the electric organs. In addition

SUBMITTER: Traeger LL 

PROVIDER: S-EPMC5498108 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature