Serum 25-hydroxyvitamin D, vitamin D binding protein, and prostate cancer risk in black men.

ABSTRACT:

Background

Few studies have prospectively examined the relationship between vitamin D status and prostate cancer risk in black men, a group at high risk for both low vitamin D status and prostate cancer.

Methods

Among black men in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, we identified 226 prostate cancer cases and 452 controls matched on age at randomization (±5 years), date of blood draw (±30 days), calendar year of cohort entry, and time since baseline prostate cancer screening (±1 year). Conditional logistic regression was used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) for the associations between serum 25-hydroxyvitamin D [25(OH)D], vitamin D binding protein (DBP), the 25(OH)D:DBP molar ratio, and prostate cancer risk

SUBMITTER: Layne TM 

PROVIDER: S-EPMC5498231 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature