Catechol-O-Methyltransferase Genotypes and Parenting Influence on Long-Term Executive Functioning After Moderate to Severe Early Childhood Traumatic Brain Injury: An Exploratory Study.

ABSTRACT:

Objectives

To examine catechol-O-methyltransferase (COMT) rs4680 genotypes as moderators of the effects of parenting style on postinjury changes in parent behavior ratings of executive dysfunction following moderate to severe early childhood traumatic brain injury.

Setting

Research was conducted in an outpatient setting.

Participants

Participants included children admitted to hospital with moderate to severe traumatic brain injury (n = 55) or orthopedic injuries (n = 70) between ages 3 and 7 years.

Design

Prospective cohort followed over 7 years postinjury.

Main measures

Parenting Practices Questionnaire and the Behavior Rating Inventory of Executive Functioning obtained at baseline, 6, 12, and 18 months, and 3.5 and 6.8 years postinjury. DNA was collect

SUBMITTER: Kurowski BG 

PROVIDER: S-EPMC5498281 | biostudies-literature | 2017 Nov/Dec

REPOSITORIES: biostudies-literature