Factors Associated with Frailty and Its Trajectory among Patients on Hemodialysis.

ABSTRACT:

Background and objectives

Frailty is common among patients on hemodialysis and associated with adverse outcomes. However, little is known about changes in frailty over time and the factors associated with those changes.

Design, setting, participants, & measurements

To address these questions, we examined 762 participants in the A Cohort to Investigate the Value of Exercise/Analyses Designed to Investigate the Paradox of Obesity and Survival in ESRD cohort study, among whom frailty was assessed at baseline and 12 and 24 months. We used ordinal generalized estimating equations analyses and modeled frailty (on a scale from zero to five possible components) and death during follow-up.

Results

The mean frailty score at baseline was 1.9, and the distribution of frailty scor

SUBMITTER: Johansen KL 

PROVIDER: S-EPMC5498360 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature