Dysphagia in Perry Syndrome: Pharyngeal Pressure in Two Cases.

ABSTRACT:

Background

To investigate the impact of dysphagia in Perry syndrome (PS), an autosomal dominant parkinsonism caused by mutation of DCTN1, which is associated with hypoventilation, depression, and weight loss.

Case presentation

We used tongue pressure measurements and manofluorography to investigate swallowing function in 2 patients with PS. Case 1, a 60-year-old male showing parkinsonism, and case 2, a 49-year-old male admitted with pneumonia, were diagnosed as having PS based on the DCTN1 gene analysis. Case 1 showed a pharyngeal retention of the bolus on videofluorography (VF) and a few swallows were required for its passage into the esophagus. However, tongue pressure and manometry were within the normal range. This patient could eat a normal diet under supervision. Case

SUBMITTER: Umemoto G 

PROVIDER: S-EPMC5498940 | biostudies-literature | 2017 May-Aug

REPOSITORIES: biostudies-literature