Genome-scale analysis of regulatory protein acetylation enzymes from photosynthetic eukaryotes.

ABSTRACT:

Background

Reversible protein acetylation occurring on Lys-N^e has emerged as a key regulatory post-translational modification in eukaryotes. It is mediated by two groups of enzymes: lysine acetyltransferases (KATs) and lysine deacetylases (KDACs) that catalyze the addition and removal of acetyl groups from target proteins. Estimates indicate that protein acetylation is second to protein phosphorylation in abundance, with thousands of acetylated sites now identified in different subcellular compartments. Considering the important regulatory role of protein phosphorylation, elucidating the diversity of KATs and KDACs across photosynthetic eukaryotes is essential in furthering our understanding of the impact of reversible protein acetylation on plant cell processes.

Resu

SUBMITTER: Uhrig RG 

PROVIDER: S-EPMC5499015 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature