Management of frailty: a protocol of a network meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Frailty is a common syndrome affecting 5-17% of community-dwelling older adults. Various interventions are used to prevent or treat frailty. Given the diversity of singular and multi-faceted frailty interventions, not all of them have been compared in head-to-head studies. Network meta-analyses provide an approach to simultaneous consideration of the relative effectiveness of multiple treatment alternatives. This systematic review and network meta-analysis of RCTs aims to determine the comparative effect of interventions targeting the prevention or treatment of frailty.

Method

We will identify relevant RCTs, in any language and publication date, by a systematic search of databases including MEDLINE, EMBASE, CINAHL, AMED, the Cochrane Central Registry of Controlled

SUBMITTER: Negm AM 

PROVIDER: S-EPMC5499023 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature