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Impact of body size, nutrition and socioeconomic position in early life on the epigenome: a systematic review protocol.


ABSTRACT:

Background

Body size, nutrition and socioeconomic position (SEP) in early life have been associated with a range of later life health outcomes. Epigenetic regulation is one mechanism through which these early life factors may impact later life health. The aim of this review protocol is to outline procedures to document the influence of body size, nutrition and SEP in early life on the epigenome.

Methods

MEDLINE, Embase and BIOSIS will be systematically searched using pre-defined keywords. Additional studies will be identified through manual searching of reference lists. Two independent researchers will assess the eligibility and quality of each study, with disagreements being resolved through discussion or a third reviewer. Studies will be included if they have epigenetic ma

SUBMITTER: Maddock J 

PROVIDER: S-EPMC5499029 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature