Genome-wide analysis of cis-regulatory element structure and discovery of motif-driven gene co-expression networks in grapevine.

ABSTRACT: Coordinated transcriptional and metabolic reprogramming ensures a plant's continued growth and survival under adverse environmental conditions. Transcription factors (TFs) act to modulate gene expression through complex cis-regulatory element (CRE) interactions. Genome-wide analysis of known plant CREs was performed for all currently predicted protein-coding gene promoters in grapevine (Vitis vinifera L.). Many CREs such as abscisic acid (ABA)-responsive, drought-responsive, auxin-responsive, and evening elements, exhibit bona fide CRE properties such as strong position bias towards the transcription start site (TSS) and over-representation when compared with random promoters. Genes containing these CREs are enriched in a large repertoire of plant biological pathways. Large-scale transcrip

SUBMITTER: Wong DCJ 

PROVIDER: S-EPMC5499852 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature