Possible Risk Factors of Pulmonary Metastases in Patients With International Federation of Gynecology and Obstetrics Stage I Endometrioid-Type Endometrial Cancer.

ABSTRACT:

Objective

Limited data have been obtained in regard to pulmonary metastasis (PM) in patients with stage I endometrial cancer. The aims of the study were (1) to present the clinical and pathological characteristics of patients with PM in the setting of stage I endometrioid-type endometrial cancer (EEC) and (2) to define possible factors that may be used to predict PM.

Methods

Six hundred thirty patients with stage I EEC, including 12 with PM, 19 with extra-PM (EPM), and 599 with no recurrence, were observed. Paired samples of primary and metastatic tumors from a patient were used for exome sequencing to identify potential gene mutations associated with PM.

Results

There was no significant difference in the age, Ki-67, lymphatic vascular space invasion, and grade 3 amon

SUBMITTER: Jiang W 

PROVIDER: S-EPMC5499968 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature