Use of warm carbon dioxide insufflators does not affect intra-colonic gas temperature and has no effect on polyp detection rate during colonoscopy - a randomized controlled trial.

ABSTRACT:

Background and study aims

Methods to improve polyp detection during colonoscopy have been investigated, with conflicting results for warm water irrigation. Carbon Dioxide (CO ₂₎ warmed to 37 °C may have similar or more pronounced effects on bowel motility. This study aimed to assess whether warmed CO ₂ would improve polyp detection compared to room temperature air insufflation.

Patients and methods

 This was a double-blind, randomized controlled trial that enrolled 204 patients undergoing screening or surveillance outpatient colonoscopy. The primary outcome was polyp per patient detection rate. Secondary outcomes included adenoma per patient detection rates, bowel spasm, and patient comfort.

Results

 The trial was terminated after an interim anal

SUBMITTER: Patel AM 

PROVIDER: S-EPMC5500117 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature