Tandem neopentyl glycol maltosides (TNMs) for membrane protein stabilisation.

ABSTRACT: A novel class of detergents, designated tandem neopentyl glycol maltosides (TNMs), were evaluated with four target membrane proteins. The best detergent varied depending on the target, but TNM-C12L and TNM-C11S were notable for their ability to confer increased membrane protein stability compared to DDM. These agents have potential for use in membrane protein research.

SUBMITTER: Bae HE 

PROVIDER: S-EPMC5500197 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature