Cardiovascular risk associated with high sodium-containing drugs: A systematic review.

ABSTRACT:

Background

Excess dietary sodium is associated with increased blood pressure (BP). Some drugs are associated with high sodium intake (in particular effervescent tablets), but the cardiovascular risk associated with such high sodium-containing drugs (HSCD) is largely underevaluated.

Objectives

To summarize the evidence for a potential cardiovascular risk associated with exposure to HSCD, and to highlight possible risk factors associated with this iatrogenic issue; in general and/or specific populations.

Methods

We conducted a systematic review, by searching electronic databases including MEDLINE, EMBASE, Web of Science, CENTRAL and grey literature between 1960 and 2015. We included studies that reported modification of cardiovascular parameters or incidence/prevalence

SUBMITTER: Perrin G 

PROVIDER: S-EPMC5500347 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature