Virological failure and all-cause mortality in HIV-positive adults with low-level viremia during antiretroviral treatment.

ABSTRACT:

Objective

Although most HIV-infected individuals achieve undetectable viremia during antiretroviral therapy (ART), a subset have low-level viremia (LLV) of varying duration and magnitude. The impact of LLV on treatment outcomes is unclear. We investigated the association between LLV and virological failure and/or all-cause mortality among Swedish patients receiving ART.

Methods

HIV-infected patients from two Swedish HIV centers were identified from the nationwide register InfCare HIV. Subjects aged ≥15 years with triple agent ART were included at 12 months after treatment initiation if ≥2 following viral load measurements were available. Patients with 2 consecutive HIV RNA values ≥1000 copies/mL at this time point were excluded. Participants were stratified into four categor

SUBMITTER: Elvstam O 

PROVIDER: S-EPMC5500364 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature