In-vivo X-ray Dark-Field Chest Radiography of a Pig.

ABSTRACT: X-ray chest radiography is an inexpensive and broadly available tool for initial assessment of the lung in clinical routine, but typically lacks diagnostic sensitivity for detection of pulmonary diseases in their early stages. Recent X-ray dark-field (XDF) imaging studies on mice have shown significant improvements in imaging-based lung diagnostics. Especially in the case of early diagnosis of chronic obstructive pulmonary disease (COPD), XDF imaging clearly outperforms conventional radiography. However, a translation of this technique towards the investigation of larger mammals and finally humans has not yet been achieved. In this letter, we present the first in-vivo XDF full-field chest radiographs (32 × 35 cm²) of a living pig, acquired with clinically compatible parameters (

SUBMITTER: Gromann LB 

PROVIDER: S-EPMC5500502 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature