Obstructive sleep apnea and objective short sleep duration are independently associated with the risk of serum vitamin D deficiency.

ABSTRACT:

Background

Studies demonstrate an association between vitamin D (25(OH)D) deficiency and sleep disturbances, such as obstructive sleep apnea (OSA) and short sleep duration. However, to date, no studies have concurrently and objectively evaluated the effect of these factors on 25(OH)D.

Objectives

To evaluate whether OSA and objective short sleep duration are independently associated with reduced 25(OH)D in an adult population sample.

Methods

A cross-sectional study included 657 individuals from the city of Sao Paulo, Brazil, as part of the ERA project. Participants fulfilled questionnaires and underwent clinical evaluation, polysomnography and blood sample collection for 25(OH)D quantification. OSA was classified into three categories (mild, moderate and severe). The r

SUBMITTER: Piovezan RD 

PROVIDER: S-EPMC5501615 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature