A method to establish the spatiotemporal evolution of task-related cortical activity from electrocorticographic signals in single trials.

ABSTRACT:

Background

Progress in neuroscience depends substantially on the ability to establish the detailed spatial and temporal sequence of neuronal population-level activity across large areas of the brain. Because there is substantial inter-trial variability in neuronal activity, traditional techniques that rely on signal averaging obscure where and when neuronal activity occurs. Thus, up to the present, it has been difficult to examine the detailed progression of neuronal activity across large areas of the brain.

New method

Here we describe a method for establishing the spatiotemporal evolution of neuronal population-level activity across large brain regions by determining exactly where and when neural activity occurs during a behavioral task in individual trials. We validate the

SUBMITTER: Coon WG 

PROVIDER: S-EPMC5501655 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature