Testicular responses to hCG stimulation at varying doses in men with spinal cord injury.

ABSTRACT:

Study design

Prospective.

Objectives

To test whether provocative stimulation of the testes identifies men with chronic spinal cord injury (SCI), a population in which serum testosterone concentrations are often depressed, possibly due to gonadal dysfunction. To accomplish this objective, conventional and lower than the conventional doses of human chorionic gonadotropin (hCG) were administered.

Methods

Thirty men with chronic SCI (duration of injury >1 year; 18 and 65 years old; 16 eugonadal (>12.1 nmol l^-1) and 14 hypogonadal (⩽12.1 nmol l^-1)) or able-bodied (AB) men (11 eugonadal and 27 hypogonadal) were recruited for the study. Stimulation tests were performed to quantify testicular responses to the intramuscular administration of hCG at three

SUBMITTER: Bauman WA 

PROVIDER: S-EPMC5501758 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature