Genomic characterization of a large plasmid containing a bla _NDM-1 gene carried on Salmonella enterica serovar Indiana C629 isolate from China.

ABSTRACT:

Background

The bla _NDM-1 gene in Salmonella species is mostly reported in clinical cases, but is rarely isolated from red and white meat in China.

Methods

A Salmonella Indiana (S. Indiana) isolate was cultured from a chicken carcass procured from a slaughterhouse in China. Antimicrobial susceptibility was tested against a panel of agents. Whole-genome sequencing of the isolate was carried out and data was analyzed.

Results

A large plasmid, denoted as plasmid pC629 (210,106 bp), containing a composite cassette, consisting of IS26-bla _NDM-1-ble _MBL -△trpF-tat-cutA-ISCR1-sul1-qacE△1-aadA2-dfrA12-intI1-IS26 was identified. The latter locus was physically linked with bla _OXA-1, bla _CTX-M-65, bla _TEM-1-encodi

SUBMITTER: Wang W 

PROVIDER: S-EPMC5501952 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature