Pediatric Stevens-Johnson syndrome and toxic epidermal necrolysis in the United States.

ABSTRACT:

Background

Little is known about the epidemiology of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in children.

Objective

We sought to determine the morbidity, mortality, and comorbid health conditions of SJS and TEN in US children.

Methods

This was a cross-sectional study of the 2009 to 2012 Nationwide Inpatient Sample, which contains a representative 20% sample of all US hospitalizations. Sociodemographics, inflation-adjusted cost, length of stay, comorbidities, and mortality were analyzed using descriptive statistics and multivariate regression analyses.

Results

The incidences of SJS, SJS-TEN, and TEN were a mean 5.3, 0.8, and 0.4 cases per million children per year in the US, respectively. Prolonged length of stay and higher costs of c

SUBMITTER: Hsu DY 

PROVIDER: S-EPMC5502094 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature