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Clinical characteristics of latent classes of CO2 hypersensitivity in adolescents and young adults.


ABSTRACT: Although breathing CO2-enriched air reliably increases anxiety, there is debate concerning the nature and specificity of CO2 hypersensitivity to panic risk and panic disorder versus anxiety disorders and related traits broadly, particularly among adolescents and emerging adults. The present study sought to clarify the association of CO2 hypersensitivity with internalizing conditions and symptoms among adolescents and young adults. Participants (N = 628) self-reported anxiety levels every 2 min while breathing air enriched to 7.5% CO2 for 8 min. Growth mixture models were used to examine the structure of anxiety trajectories during the task and the association of each trajectory with dimensional and diagnostic assessments of internalizing disorder

SUBMITTER: Rappaport LM 

PROVIDER: S-EPMC5502686 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature