Seattle Heart Failure and Proportional Risk Models Predict Benefit From Implantable Cardioverter-Defibrillators.

ABSTRACT:

Background

Recent clinical trials highlight the need for better models to identify patients at higher risk of sudden death.

Objectives

The authors hypothesized that the Seattle Heart Failure Model (SHFM) for overall survival and the Seattle Proportional Risk Model (SPRM) for proportional risk of sudden death, including death from ventricular arrhythmias, would predict the survival benefit with an implantable cardioverter-defibrillator (ICD).

Methods

Patients with primary prevention ICDs from the National Cardiovascular Data Registry (NCDR) were compared with control patients with heart failure (HF) without ICDs with respect to 5-year survival using multivariable Cox proportional hazards regression.

Results

Among 98,846 patients with HF (87,914 with ICDs and 10,

SUBMITTER: Bilchick KC 

PROVIDER: S-EPMC5502749 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature