A population-based comparative effectiveness study of chemoradiation regimens and sequences in stage III non-small cell lung cancer.

ABSTRACT:

Objectives

In patients receiving concurrent chemoradiation for locally advanced non-small cell lung cancer (NSCLC), consolidation chemotherapy is frequently given even though several randomized trials have failed to show a benefit. We explored the potential benefits of consolidation chemotherapy using a population-based comparative effectiveness approach.

Materials and methods

Surveillance, Epidemiology, and End Results-Medicare was used to identify patients with Stage III NSCLC aged ≥65 and diagnosed 2002-2009. We selected patients who received concurrent chemoradiotherapy and determined whether they were (concurrent-consolidation) or were not (concurrent-alone) treated with consolidation chemotherapy. Outcomes were overall and cancer specific survival using a conditional l

SUBMITTER: Harris JP 

PROVIDER: S-EPMC5502824 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature