Quantification of Lipid-Rich Core in Carotid Atherosclerosis Using Magnetic Resonance T₂ Mapping: Relation to Clinical Presentation.

ABSTRACT:

Objectives

The aim of this study was to: 1) provide tissue validation of quantitative T₂ mapping to measure plaque lipid content; and 2) investigate whether this technique could discern differences in plaque characteristics between symptom-related and non-symptom-related carotid plaques.

Background

Noninvasive plaque lipid quantification is appealing both for stratification in treatment selection and as a possible predictor of future plaque rupture. However, current cardiovascular magnetic resonance (CMR) methods are insensitive, require a coalesced mass of lipid core, and rely on multicontrast acquisition with contrast media and extensive post-processing.

Methods

Patients scheduled for carotid endarterectomy were recruited for 3-T carotid CMR before surger

SUBMITTER: Chai JT 

PROVIDER: S-EPMC5502905 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature