Neuronal correlates of cognitive function in patients with childhood cerebellar tumor lesions.

ABSTRACT: While it has been shown that cerebellar tumor lesions have an impact on cognitive functions, the extent to which they shape distant neuronal pathways is still largely undescribed. Thus, the present neuroimaging study was designed to investigate different aspects of cognitive function and their neuronal correlates in patients after childhood cerebellar tumor surgery. An alertness task, a working memory task and an incompatibility task were performed by 11 patients after childhood cerebellar tumor surgery and 17 healthy controls. Neuronal correlates as reflected by alterations in functional networks during tasks were assessed using group independent component analysis. We were able to identify eight networks involved during task performance: default mode network, precuneus, anterior salience

SUBMITTER: Reichert JL 

PROVIDER: S-EPMC5503240 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature