The serum 25-hydroxyvitamin D levels and hip fracture risk: a meta-analysis of prospective cohort studies.

ABSTRACT: Hip fracture has increasingly become a social and economic burden. The relationship between serum 25-hydroxyvitamin D levels and the risk of hip fracture reported by previous studies remains controversial. We searched Pubmed and Embase to identify studies reporting the relationship between serum 25-hydroxyvitamin D levels and risk of hip fracture. Fifteen prospective cohort studies with a total of 51239 participants and 3386 hip fracture cases were included. By pooling the Relative Risk of the lowest vs. the highest categories indicated that lower levels of serum 25-hydroxyvitamin D were more likely to be a risk factor for hip fracture with adjusted Relative Risk (95%Confidence Interval) of 1.58 (1.41, 1.77). Subgroup meta-analysis examining the stability of the primary results achieved th

SUBMITTER: Lv QB 

PROVIDER: S-EPMC5503658 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature