Gradients of connectivity distance are anchored in primary cortex.

ABSTRACT: Connectivity between distant cortical areas is a valuable, yet costly feature of cortical organization and is predominantly found between regions of heteromodal association cortex. The recently proposed 'tethering hypothesis' describes the emergence of long-distance connections in association cortex as a function of their spatial separation from primary cortical regions. Here, we investigate this possibility by characterizing the distance between functionally connected areas along the cortical surface. We found a systematic relationship between an area's characteristic connectivity distance and its distance from primary cortical areas. Specifically, the further a region is located from primary sensorimotor regions, the more distant are its functional connections with other areas of the cor

SUBMITTER: Oligschlager S 

PROVIDER: S-EPMC5504232 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature