Comparative proteomic profiling of the serum differentiates pancreatic cancer from chronic pancreatitis.

ABSTRACT: Finland ranks sixth among the countries having highest incidence rate of pancreatic cancer with mortality roughly equaling incidence. The average age of diagnosis for pancreatic cancer is 69 years in Nordic males, whereas the average age of diagnosis of chronic pancreatitis is 40-50 years, however, many cases overlap in age. By radiology, the evaluation of a pancreatic mass, that is, the differential diagnosis between chronic pancreatitis and pancreatic cancer is often difficult. Preoperative needle biopsies are difficult to obtain and are demanding to interpret. New blood based biomarkers are needed. The accuracy of the only established biomarker for pancreatic cancer, CA 19-9 is rather poor in differentiating between benign and malignant mass of the pancreas. In this study, we have perfo

SUBMITTER: Saraswat M 

PROVIDER: S-EPMC5504330 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature