Anorexia nervosa and cancer: a protocol for a systematic review and meta-analysis of observational studies.

ABSTRACT:

Background

Anorexia nervosa is characterized by a severe restriction of caloric intake, low body weight, fear of gaining weight or of becoming fat, and disturbance of body image. Pathogenesis of the disorder may include genetic predisposition, hormonal changes and a combination of environmental, psychosocial, and cultural factors. Cancer is the second leading cause of death worldwide. At present, no systematic reviews and meta-analyses have evaluated the risk of cancer in people with anorexia nervosa. The objective of this study will be to evaluate the association between anorexia nervosa and the risk of developing or dying from cancer.

Methods/design

This study protocol is part of a systematic collection and assessment of multiple systematic reviews and meta-analyses (umbre

SUBMITTER: Catala-Lopez F 

PROVIDER: S-EPMC5504548 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature